PARD6B antibody

• Background:

  Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.

• Synonyms:

  Partitioning defective 6 homolog beta (PAR-6 beta, PAR-6B) |PARD6B|PAR6B

• Gene ID:

  84612

• UniProt:

  Q9BYG5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Par-6 partitioning defective 6 homolog beta (C. elegans)

• Target:

  PARD6B

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF, IP, FC

• Field of Research:

  Signal Transduction, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  50-53 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF, IP, FC