PAK2 antibody

• Background:

  The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

• Synonyms:

  Serine/threonine-protein kinase PAK 2|Gamma-PAK|PAK65|S6/H4 kinase|p21-activated kinase 2 (PAK-2) |p58|PAK-2p27 (p27) |PAK-2p34 (p34) Alternative names: C-t-PAK2|PAK2

• Gene ID:

  5062

• UniProt:

  Q13177

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  P21 protein (Cdc42/Rac) -activated kinase 2

• Target:

  PAK2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Signal Transduction, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  58 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF