PAK1 antibody

• Background:

  This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Synonyms:

  Serine/threonine-protein kinase PAK 1|Alpha-PAK|p21-activated kinase 1 (PAK-1) |p65-PAK|PAK1

• Gene ID:

  5058

• UniProt:

  Q13153

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  P21 protein (Cdc42/Rac) -activated kinase 1

• Target:

  PAK1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Neuroscience, Cardiovascular, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  62 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC