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PAIP2 antibody

CAT: 0710-FNab06118Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06118Size:100 µg
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Background
Acts as a repressor in the regulation of translation initiation of poly (A) -containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly (A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly (A) RNP structure organization.
Synonyms
Polyadenylate-binding protein-interacting protein 2 (PABP-interacting protein 2, PAIP-2, Poly (A) -binding protein-interacting protein 2) |PAIP2|PAIP2A
Gene ID
51247
UniProt
Q9BPZ3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Poly (A) binding protein interacting protein 2
Target
PAIP2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
26 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF