MAPK14 antibody

• Background :

  MAPK14 (mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T (H) 17 differentiation and inflammation (PMID:22231518) . It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell (PMID:21198398) . This protein has 4 isoforms produced by alternative splicing.

• Synonyms :

  Mitogen-activated protein kinase 14 (MAP kinase 14, MAPK 14) |Cytokine suppressive anti-inflammatory drug-binding protein (CSAID-binding protein, CSBP) |MAP kinase MXI2|MAX-interacting protein 2|Mitogen-activated protein kinase p38 alpha (MAP kinase p38 alpha) |Stress-activated protein kinase 2a (SAPK2a) |MAPK14|CSBP|CSBP1|CSBP2|CSPB1|MXI2|SAPK2A

• Gene ID :

  1432

• UniProt :

  Q16539

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Mitogen-activated protein kinase 14

• Target :

  MAPK14

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IF, IHC

• Field of Research :

  Immunology, Cardiovascular, Metabolism, Signal Transduction

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:200-1:2000; IF: 1:20-1:200; IHC: 1:50-1:500

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  41 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IF, IHC

• Immunogen Sequence :

  300 to the C-terminus