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CTNND1 antibody

CAT: 0710-FNab06059Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06059Size:100 µg
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Background
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity) . Associates with and regulates the cell adhesion properties of both C-, E-and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Synonyms
Catenin delta-1|Cadherin-associated Src substrate (CAS) |p120 catenin (p120 (ctn) ) |p120 (cas) |CTNND1|KIAA0384
UniProt
O60716
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Catenin, delta 1
Target
CTNND1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IP,IHC
Field of Research
Cancer, Immunology, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
105 kDa, 66 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IP, IHC
Immunogen Sequence
470-712aa

UniProtKB · O60716

Catenin delta-1

CTND1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60716
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CTNND1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K939, O15088, O60713, O60714, O60715, O60935, Q6DHZ7, Q6RBX8, Q9UP71, Q9UP72, Q9UP73
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative initiationAlternative splicing

Biological process

Cell adhesionTranscriptionTranscription regulationWnt signaling pathway

Cellular component

Cell junctionCell membraneCytoplasmMembraneNucleus

Domain

Coiled coilRepeat

Disease

Disease variantEctodermal dysplasia

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