SPP1 antibody

CAT: 0710-FNab06033Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab06033Size:100 µg
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Background
Osteopontin (OPN), also known as SPP1, is a secreted glycophosphoprotein that belongs to the small integrin-binding ligand N-linked glycoprotein (SIBLING) family. Originally isolated from bone, OPN has been found in kidney, vascular tissues, biological fluids, and various tumor tissues (PMID: 15138464; 16406521) . OPN can interact with CD44 and integrins and regulate diverse biological processes. It has a multifaceted role in bone development and remodeling, and is also involved in the inflammatory and immune response, oncogenesis and cancer progression.
Synonyms
Osteopontin|Bone sialoprotein 1|Nephropontin|Secreted phosphoprotein 1 (SPP-1) |Urinary stone protein|Uropontin|SPP1|BNSP|OPN
Gene ID
6696
UniProt
P10451
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Secreted phosphoprotein 1
Target
SPP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IF
Field of Research
Neuroscience, Stem Cells, Immunology, Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
66 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, IF

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