SPP1 antibody

• Background:

  Osteopontin (OPN), also known as SPP1, is a secreted glycophosphoprotein that belongs to the small integrin-binding ligand N-linked glycoprotein (SIBLING) family. Originally isolated from bone, OPN has been found in kidney, vascular tissues, biological fluids, and various tumor tissues (PMID: 15138464; 16406521) . OPN can interact with CD44 and integrins and regulate diverse biological processes. It has a multifaceted role in bone development and remodeling, and is also involved in the inflammatory and immune response, oncogenesis and cancer progression.

• Synonyms:

  Osteopontin|Bone sialoprotein 1|Nephropontin|Secreted phosphoprotein 1 (SPP-1) |Urinary stone protein|Uropontin|SPP1|BNSP|OPN

• Gene ID:

  6696

• UniProt:

  P10451

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Secreted phosphoprotein 1

• Target:

  SPP1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC, WB, IF

• Field of Research:

  Neuroscience, Stem Cells, Immunology, Cardiovascular

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  66 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC, WB, IF