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OSBPL10 antibody

CAT: 0710-FNab06017Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06017Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (PubMed:23934110) (Probable) . Plays a role in negative regulation of lipid biosynthesis (PubMed:19554302) . Negatively regulates APOB secretion from hepatocytes (PubMed:19554302, PubMed:22906437) . Binds cholesterol and acidic phospholipids (PubMed:22906437) . Also binds 25-hydroxycholesterol (PubMed:17428193) . Binds phosphatidylserine (PubMed:23934110) .
Synonyms
Oxysterol-binding protein-related protein 10 (ORP-10, OSBP-related protein 10) |OSBPL10|ORP10|OSBP9
Gene ID
114884
UniProt
Q9BXB5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Oxysterol binding protein-like 10
Target
OSBPL10
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
75-80 kDa, 64 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP

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