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OCRL antibody

CAT: 0710-FNab05959Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05959Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate (PubMed:25869668, PubMed:7761412, PubMed:9430698) . May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly (PubMed:22228094, PubMed:22543976) .
Synonyms
Inositol polyphosphate 5-phosphatase OCRL|Inositol polyphosphate 5-phosphatase OCRL-1 (OCRL-1) |Lowe oculocerebrorenal syndrome protein|Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase|OCRL|OCRL1
Gene ID
4952
UniProt
Q01968
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Oculocerebrorenal syndrome of Lowe
Target
OCRL
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
105 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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