NR3C2 antibody

• Background:

  Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.

• Synonyms:

  Mineralocorticoid receptor (MR) |Nuclear receptor subfamily 3 group C member 2|NR3C2|MCR|MLR

• Gene ID:

  4306

• UniProt:

  P08235

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Nuclear receptor subfamily 3, group C, member 2

• Target:

  NR3C2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF, IP

• Field of Research:

  Cardiovascular, Metabolism, Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:500-1:1000 ; IHC: 1:20-1:200; IF: 1:10-1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  107 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF, IP