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NPLOC4 antibody

CAT: 0710-FNab05821Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05821Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity) .
Synonyms
Nuclear protein localization protein 4 homolog (Protein NPL4) |NPLOC4|KIAA1499|NPL4
Gene ID
55666
UniProt
Q8TAT6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Nuclear protein localization 4 homolog
Target
NPLOC4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
68 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP, IHC

UniProtKB · Q8TAT6

Nuclear protein localization protein 4 homolog

NPL4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8TAT6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NPLOC4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Protein NPL4
EC number
—
Processing
—
Secondary accessions
Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Acetylation

Coding sequence diversity

Alternative splicing

Molecular function

Chaperone

Cellular component

CytoplasmEndoplasmic reticulumNucleus

Ligand

Metal-bindingZinc

Biological process

Ubl conjugation pathway

Domain

Zinc-finger

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