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NPL antibody

CAT: 0710-FNab05820Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05820Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (By similarity) .
Synonyms
N-acetylneuraminate lyase (NALase) |N-acetylneuraminate pyruvate-lyase|N-acetylneuraminic acid aldolase|Sialate lyase|Sialate-pyruvate lyase|Sialic acid aldolase|Sialic acid lyase|NPL|C1orf13
Gene ID
80896
UniProt
Q9BXD5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
Target
NPL
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
35 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF

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