NET1 antibody

• Background:

  Acts as guanine nucleotide exchange factor(GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.

• Synonyms:

  Neuroepithelial cell-transforming gene 1 protein|Proto-oncogene p65 Net1|Rho guanine nucleotide exchange factor 8|NET1|ARHGEF8

• Gene ID:

  10276

• UniProt:

  Q7Z628

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  neuroepithelial cell transforming 1

• Target:

  NET1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF, IHC

• Field of Research:

  Signal Transduction, Metabolism, Cancer, Immunology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  62-68 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

• CAS Number:

  9007-83-4