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NDUFS3 antibody

CAT: 0710-FNab05630Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05630Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I) . Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.
Synonyms
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial|Complex I-30kD (CI-30kD) |NADH-ubiquinone oxidoreductase 30 kDa subunit|NDUFS3
Gene ID
4722
UniProt
O75489
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
Target
NDUFS3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
30 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · O75489

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

NDUS3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75489
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NDUFS3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
7.1.1.2
Processing
Precursor
Secondary accessions
B2R9J1, B4DFM8, Q9UNQ8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Disease variantPrimary mitochondrial disease

Biological process

Electron transportRespiratory chainTransport

Cellular component

MembraneMitochondrionMitochondrion inner membrane

Ligand

NADUbiquinone

Molecular function

OxidoreductaseTranslocase

Domain

Transit peptide

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