NDC80 antibody
CAT:
710-FNab05599
Size:
100 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NDC80 antibody
- Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity(PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore(PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules(PubMed:23085020).
- Synonyms: Kinetochore protein NDC80 homolog|Highly expressed in cancer protein|Kinetochore protein Hec1 (HsHec1)|Kinetochore-associated protein 2|Retinoblastoma-associated protein HEC|NDC80|HEC|HEC1|KNTC2
- CAS Number: 9007-83-4
- Gene ID: 10403
- UniProt: O14777
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Immunogen: NDC80 homolog, kinetochore complex component
- Target: NDC80
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, WB, IHC, IP
- Field of Research: Cell Division and Proliferation, Metabolism
- Purification: Immunogen affinity purified
- Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 76 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)