Products for Research Use Only
RegisterLogin

NCAM1 antibody

CAT: 0710-FNab05575Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab05575Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Neural cell adhesion molecule 1 (NCAM1, also known as CD56) is a cell adhesion glycoprotein of the immunoglobulin (Ig) superfamily. It is a multifunction protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM1 is expressed on human neurones, glial cells, skeletal muscle cells, NK cells and a subset of T cells, and the expression is observed in a wide variety human tumors, including myeloma, myeloid leukemia, neuroendocrine tumors, Wilms' tumor, neuroblastoma, and NK/T cell lymphomas. Three major isoforms of NCAM1, with molecular masses of 120, 140, and 180 kDa, are generated by alternative splicing of mRNA (PMID: 9696812) . The glycosylphosphatidylinositol (GPI) -anchored NCAM120 and the transmembrane NCAM140 and NCAM180 consist of five Ig-like domains and two fibronection-type III repeats (FNIII) . All three forms can be posttranslationally modified by addition of polysialic acid (PSA) (PMID: 14976519) . Several other isofroms have also been described (PMID: 1856291) .
Synonyms
Neural cell adhesion molecule 1 (N-CAM-1, NCAM-1) |NCAM1|NCAM
Gene ID
4684
UniProt
P13591
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Neural cell adhesion molecule 1
Target
NCAM1
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Immunology, Cancer, Developmental biology, Neuroscience, Stem Cells
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:10000; IHC: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
0D10
Tested Applications
ELISA, WB, IHC

Related Products

CatalogName
P1167-01Recombinant Human NCAM1
FNab05576NCAM2 antibody
F700-30254-01FineTest®700 Anti-Human CD56/NCAM Antibody (B-A19)
F647-30254-01FineTest®647 Anti-Human CD56/NCAM Antibody (B-A19)
FV450-30040-01FineTest®Violet 450 Anti-Human CD56/NCAM Antibody (FN511H)
PC55-30254-01PE-Cy5.5 Anti-Human CD56/NCAM Antibody (B-A19)
Pr22493-01Recombinant Human NCAM-1
EH1411Human NCAM2 (Neural cell adhesion molecule 2) ELISA Kit
QT-EH1411Human NCAM2 (Neural cell adhesion molecule 2) QuickTest ELISA Kit
FNab11062CA125 antibody (capture antibody)

Alternative Products

CatalogName
GTR18025524Ncam1 Antibody

Popular Products