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MYH9 antibody

CAT: 0710-FNab05482Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05482Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10.
Synonyms
Myosin-9|Cellular myosin heavy chain, type A|Myosin heavy chain 9|Myosin heavy chain, non-muscle IIa|Non-muscle myosin heavy chain A (NMMHC-A) |Non-muscle myosin heavy chain IIa (NMMHC II-a, NMMHC-IIA) |MYH9
Gene ID
4627
UniProt
P35579
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Myosin, heavy chain 9, non-muscle
Target
MYH9
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB
Field of Research
Immunology, Developmental biology
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:5000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
224 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
2E11
Tested Applications
ELISA, WB

UniProtKB · P35579

Myosin-9

MYH9_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35579
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MYH9
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K6E4, O60805, Q60FE2, Q86T83
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoproteinUbl conjugation

Molecular function

Actin-bindingCalmodulin-bindingHost cell receptor for virus entryMotor proteinMyosinReceptor

Disease

Alport syndromeCataractDeafnessDisease variantNon-syndromic deafness

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Biological process

Cell adhesionCell shape

Cellular component

Cell membraneCytoplasmCytoplasmic vesicleCytoskeletonMembrane

Domain

Coiled coil

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