MUTYH antibody

CAT: 0710-FNab05445Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab05445Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.

Synonyms

Adenine DNA glycosylase|MutY homolog (hMYH) |MUTYH|MYH

Gene ID

4595

UniProt

Q9UIF7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

MutY homolog (E. coli)

Target

MUTYH

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

53-64 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

UniProtKB · Q9UIF7

Adenine DNA glycosylase

MUTYH_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9UIF7
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: MUTYH
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.2.2.31
Processing: —
Secondary accessions: D3DPZ4, Q15830, Q9UBP2, Q9UBS7, Q9UIF4, Q9UIF5, Q9UIF6

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

4Fe-4SIronIron-sulfurMetal-binding

Coding sequence diversity

Alternative splicing

Disease

Disease variantTumor suppressor

Biological process

DNA damageDNA repair

Molecular function

GlycosidaseHydrolase

Cellular component

MitochondrionNucleus

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Alternative Products

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70R-18684	MUTYH antibody