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MTM1 antibody

CAT: 0710-FNab05406Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05406Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI (3,5) P2) . Has also been shown to dephosphorylate phosphotyrosine-and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.
Synonyms
Myotubularin|Phosphatidylinositol-3,5-bisphosphate 3-phosphatase|Phosphatidylinositol-3-phosphate phosphatase|MTM1|CG2
Gene ID
4534
UniProt
Q13496
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Myotubularin 1
Target
MTM1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Stem Cells, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
63 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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