MRAP antibody

• Background:

  Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R) . Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH) . May be involved in the intracellular trafficking pathways in adipocyte cells.

• Synonyms:

  Melanocortin-2 receptor accessory protein|B27|Fat cell-specific low molecular weight protein|Fat tissue-specific low MW protein|MRAP|C21orf61|FALP

• Gene ID:

  56246

• UniProt:

  Q8TCY5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Melanocortin 2 receptor accessory protein

• Target:

  MRAP

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Neuroscience, Signal Transduction, Immunology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  12 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC