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MPZL1 antibody

CAT: 0710-FNab05300Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05300Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
Synonyms
Myelin protein zero-like protein 1|Protein zero-related|MPZL1|PZR
Gene ID
9019
UniProt
O95297
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Myelin protein zero-like 1
Target
MPZL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
16 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · O95297

Myelin protein zero-like protein 1

MPZL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95297
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MPZL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2REB9, B2REC0, Q5R332, Q8IX11, Q9BWZ3, Q9NYK4, Q9UL20
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix

Cellular component

Membrane

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