Glycodeoxycholate (Sodium)

Glycodeoxycholate (Sodium)

• CAS Number: 16409-34-0
• UNSPSC Description: Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) is a bile salt. Glycodeoxycholate Sodium has cytotoxicity to cancer cell, changes the permeability of the pancreatic duct and decreases glucose levels[1][2][3].
• Target Antigen: Endogenous Metabolite
• Type: Natural Products
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/Glycodeoxycholate_Sodium.html
• Purity: 98.02
• Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 100 mg/mL (ultrasonic)
• Smiles: O=C(O[Na])CNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)=O
• Molecular Weight: 471.61
• References & Citations: [1]Brayden DJ, et al. Sodium glycodeoxycholate and sodium deoxycholate as epithelial permeation enhancers: in vitro and ex vivo intestinal and buccal bioassays. Eur J Pharm Sci. 2021 Apr 1;159:105737.|[2]Farmer RC, et al. Effects of bile salts on permeability and morphology of main pancreatic duct in cats. Dig Dis Sci. 1984 Aug;29(8):740-51. |[3]Illum L, et al. Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance the nasal absorption of polypeptides. Int J Pharm. 2001 Jul 3;222(1):109-19.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported