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Glycodeoxycholate (Sodium)

CAT: 0804-HY-N1427-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1427-01Size:100 mg
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Description
Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) is a bile salt. Glycodeoxycholate Sodium has cytotoxicity to cancer cell, changes the permeability of the pancreatic duct and decreases glucose levels[1][2][3].
CAS Number
16409-34-0
Product Name Alternative
Sodium glycyldeoxycholate
UNSPSC
12352211
Hazard Statement
H302, H312, H332
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Glycodeoxycholate_Sodium.html
Purity
99.92
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O[Na])CNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)=O
Molecular Formula
C26H42NNaO5
Molecular Weight
471.61
Precautions
H302, H312, H332
References & Citations
[1]Brayden DJ, et al. Sodium glycodeoxycholate and sodium deoxycholate as epithelial permeation enhancers: in vitro and ex vivo intestinal and buccal bioassays. Eur J Pharm Sci. 2021 Apr 1;159:105737.|[2]Farmer RC, et al. Effects of bile salts on permeability and morphology of main pancreatic duct in cats. Dig Dis Sci. 1984 Aug;29 (8) :740-51. |[3]Illum L, et al. Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance the nasal absorption of polypeptides. Int J Pharm. 2001 Jul 3;222 (1) :109-19.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; Microbial Metabolite