Glycodeoxycholate (Sodium)

• Description:

  Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) is a bile salt. Glycodeoxycholate Sodium has cytotoxicity to cancer cell, changes the permeability of the pancreatic duct and decreases glucose levels[1][2][3].

• Product Name Alternative:

  Sodium glycyldeoxycholate

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H312, H332

• Target:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/Glycodeoxycholate_Sodium.html

• Purity:

  99.92

• Solubility:

  DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (O[Na]) CNC (CC[C@@H] (C) [C@H]1CC[C@@]2 ([H]) [C@]3 ([H]) CC[C@]4 ([H]) C[C@H] (O) CC[C@]4 (C) [C@@]3 ([H]) C[C@H] (O) [C@]12C) =O

• Molecular Formula:

  C26H42NNaO5

• Molecular Weight:

  471.61

• Precautions:

  H302, H312, H332

• References & Citations:

  [1]Brayden DJ, et al. Sodium glycodeoxycholate and sodium deoxycholate as epithelial permeation enhancers: in vitro and ex vivo intestinal and buccal bioassays. Eur J Pharm Sci. 2021 Apr 1;159:105737.|[2]Farmer RC, et al. Effects of bile salts on permeability and morphology of main pancreatic duct in cats. Dig Dis Sci. 1984 Aug;29 (8) :740-51. |[3]Illum L, et al. Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance the nasal absorption of polypeptides. Int J Pharm. 2001 Jul 3;222 (1) :109-19.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite; Microbial Metabolite

• CAS Number:

  16409-34-0