MPRIP antibody

• Background :

  Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.

• Synonyms :

  Myosin phosphatase Rho-interacting protein (M-RIP) |Rho-interacting protein 3 (RIP3) |p116Rip|MPRIP|KIAA0864|MRIP|RHOIP3

• Gene ID :

  23164

• UniProt :

  Q6WCQ1

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Myosin phosphatase Rho interacting protein

• Target :

  MPRIP

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IF, IP

• Field of Research :

  Signal Transduction

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  116-140 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IF, IP