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MME antibody

CAT: 0710-FNab05232Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05232Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MME is also names as neprilysin, CALLA, NEP, SFE, CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas (PMID:15286660) .This antibody is specific to MME.
Synonyms
Neprilysin|Atriopeptidase|Common acute lymphocytic leukemia antigen (CALLA) |Enkephalinase|Neutral endopeptidase 24.11 (NEP, Neutral endopeptidase) |Skin fibroblast elastase (SFE) |MME|EPN
Gene ID
4311
UniProt
P08473
Host
Mouse
Reactivity
Human, Pig
Immunogen
Membrane metallo-endopeptidase
Target
MME
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, IHC, WB
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Neuroscience, Stem Cells
Purification
Protein A+G purification
Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
90-110 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
1H6
Tested Applications
ELISA, IHC, WB

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