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MMADHC antibody

CAT: 0710-FNab05228Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05228Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Involved in cobalamin metabolism (PubMed:18385497, PubMed:23415655, PubMed:24722857, PubMed:26364851) . Plays a role in regulating the biosynthesis of two coenzymes, methylcobalamin and adenosylcobalamin (PubMed:18385497, PubMed:24722857) . Plays a role in regulating the proportion of methylcobalamin and adenosylcobalamin (PubMed:23415655, PubMed:24722857) . Promotes oxidation of cob (II) alamin bound to MMACHC (PubMed:26364851) .
Synonyms
Cobalamin trafficking protein CblD|CblD|Methylmalonic aciduria and homocystinuria type D protein, mitochondrial|MMADHC|C2orf25|CL25022
Gene ID
27249
UniProt
Q9H3L0
Host
Rabbit
Reactivity
Human
Immunogen
Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
Target
MMADHC
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
33 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB