MRTFA antibody

• Background :

  Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation (By similarity) .

• Synonyms :

  Myocardin-related transcription factor A (MRTF-A) |MKL/myocardin-like protein 1|Megakaryoblastic leukemia 1 protein|Megakaryocytic acute leukemia protein|MRTFA|KIAA1438|MAL|MKL1

• Gene ID :

  57591

• UniProt :

  Q969V6

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Megakaryoblastic leukemia (translocation) 1

• Target :

  MRTFA

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IF

• Field of Research :

  Stem Cells, Cardiovascular, Metabolism, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  145 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IF