MIB2 antibody

• Background:

  E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity) .

• Synonyms:

  E3 ubiquitin-protein ligase MIB2|Mind bomb homolog 2|Novel zinc finger protein (Novelzin) |Putative NF-kappa-B-activating protein 002N|RING-type E3 ubiquitin transferase MIB2|Skeletrophin|Zinc finger ZZ type with ankyrin repeat domain protein 1|MIB2|SKD|ZZANK1

• Gene ID:

  142678

• UniProt:

  Q96AX9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Mindbomb homolog 2 (Drosophila)

• Target:

  MIB2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  74 kDa, 82 kDa, 110 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB