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MBD3 antibody

CAT: 0710-FNab05035Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05035Size:100 µg
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Background
Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384) . Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro) . Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175) . Recruits histone deacetylases and DNA methyltransferases.
Synonyms
Methyl-CpG-binding domain protein 3|Methyl-CpG-binding protein MBD3|MBD3
Gene ID
53615
UniProt
O95983
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Methyl-CpG binding domain protein 3
Target
MBD3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
33 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP

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