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MBD2 antibody

CAT: 0710-FNab05034Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05034Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
Synonyms
Methyl-CpG-binding domain protein 2|Demethylase (DMTase) |Methyl-CpG-binding protein MBD2|MBD2
Gene ID
8932
UniProt
Q9UBB5
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Methyl-CpG binding domain protein 2
Target
MBD2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
43-45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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