MAGEC2 antibody

• Background:

  Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.

• Synonyms:

  Melanoma-associated antigen C2|Cancer/testis antigen 10 (CT10) |Hepatocellular carcinoma-associated antigen 587|MAGE-C2 antigen|MAGE-E1 antigen|MAGEC2|HCA587|MAGEE1

• Gene ID:

  51438

• UniProt:

  Q9UBF1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Melanoma antigen family C, 2

• Target:

  MAGEC2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC

• Field of Research:

  Cancer, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  IHC: 1:20 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  41 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC