MAGEA1 antibody

• Background:

  May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

• Synonyms:

  Melanoma-associated antigen 1|Antigen MZ2-E|Cancer/testis antigen 1.1 (CT1.1) |MAGE-1 antigen|MAGEA1|MAGE1|MAGE1A

• Gene ID:

  4100

• UniProt:

  P43355

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Melanoma antigen family A, 1 (directs expression of antigen MZ2-E)

• Target:

  MAGEA1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Cancer, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  43 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB