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LRWD1 antibody

CAT: 0710-FNab04867Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04867Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
Synonyms
Leucine-rich repeat and WD repeat-containing protein 1|Centromere protein 33 (CENP-33) |Origin recognition complex-associated protein (ORC-associated protein, ORCA) |LRWD1|CENP-33|ORCA
Gene ID
222229
UniProt
Q9UFC0
Host
Rabbit
Reactivity
Human
Immunogen
Leucine-rich repeats and WD repeat domain containing 1
Target
LRWD1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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