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LITAF antibody

CAT: 0710-FNab04798Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04798Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD) . Multiple alternatively spliced transcript variants have been found for this gene.
Synonyms
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS-induced TNF-alpha factor) |Small integral membrane protein of lysosome/late endosome|p53-induced gene 7 protein|LITAF|PIG7|SIMPLE
Gene ID
9516
UniProt
Q99732
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Lipopolysaccharide-induced TNF factor
Target
LITAF
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
20 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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