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LINGO1 antibody

CAT: 0710-FNab04792Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04792Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321) . Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088) . Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity) .
Synonyms
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1|Leucine-rich repeat and immunoglobulin domain-containing protein 1|Leucine-rich repeat neuronal protein 1|Leucine-rich repeat neuronal protein 6A|LINGO1|LERN1|LRRN6A
Gene ID
84894
UniProt
Q96FE5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Leucine rich repeat and Ig domain containing 1
Target
LINGO1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Stem Cells, Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
83 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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