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KLF15 antibody

CAT: 0710-FNab04600Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04600Size:100 µg
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Background
Transcriptional regulator that binds to the GA element of the CLCNKA promoter. Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart (By similarity) . Is a repressor of CTGF expression, involved in the control of cardiac fibrosis. It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4 (By similarity) . Involved in podocyte differentiation (By similarity) . Inhibits MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation.
Synonyms
Krueppel-like factor 15|Kidney-enriched krueppel-like factor|KLF15|KKLF
Gene ID
28999
UniProt
Q9UIH9
Host
Mouse
Reactivity
Human
Immunogen
Kruppel-like factor 15
Target
KLF15
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB
Field of Research
Cardiovascular, Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
1C10
Tested Applications
ELISA, WB
Immunogen Sequence
1-416aa

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