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KLF10 antibody

CAT: 0710-FNab04597Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04597Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity) . May play a role in the cell cycle regulation.
Synonyms
Krueppel-like factor 10|EGR-alpha|Transforming growth factor-beta-inducible early growth response protein 1 (TGFB-inducible early growth response protein 1, TIEG-1) |KLF10|TIEG|TIEG1
Gene ID
7071
UniProt
Q13118
Host
Rabbit
Reactivity
Human
Immunogen
Kruppel-like factor 10
Target
KLF10
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IP
Field of Research
Cardiovascular, Metabolism, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
52 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IP

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