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WASHC4 antibody

CAT: 0710-FNab04539Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04539Size:100 µg
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Background
Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in the regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093) .
Synonyms
WASH complex subunit 4|Strumpellin and WASH-interacting protein (SWIP) |WASH complex subunit SWIP|WASHC4|KIAA1033
Gene ID
23325
UniProt
Q2M389
Host
Rabbit
Reactivity
Human
Immunogen
KIAA1033
Target
WASHC4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
136 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · Q2M389

WASH complex subunit 4

WASC4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q2M389
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WASHC4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q2NL83, Q8IW61, Q8N5W7, Q9NVD6, Q9UPW7
Protein keywords

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Domain

Coiled coil

Disease

Disease variantIntellectual disability

Cellular component

Endosome

Biological process

Protein transportTransport

Technical term

Proteomics identificationReference proteome

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NBP2-44290BRabbit Polyclonal WASHC4 Antibody [Biotin]
NBP2-44291IRRabbit Polyclonal WASHC4 Antibody [DyLight 755]
NBP2-44290RRabbit Polyclonal WASHC4 Antibody [DyLight 550]
NBP2-44291UVRabbit Polyclonal WASHC4 Antibody [DyLight 350]
NBP2-44290FRRabbit Polyclonal WASHC4 Antibody [DyLight 680]
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