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WASHC3 antibody

CAT: 0710-FNab01361Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01361Size:100 µg
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Background
Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093) .
Synonyms
WASH complex subunit 3|Coiled-coil domain-containing protein 53|WASHC3
Gene ID
51019
UniProt
Q9Y3C0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Coiled-coil domain containing 53
Target
WASHC3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · Q9Y3C0

WASH complex subunit 3

WASC3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y3C0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WASHC3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2RC74, Q53FF0, Q6IAI4, Q96QK0
Protein keywords

PTM

Acetylation

Domain

Coiled coil

Cellular component

Endosome

Biological process

Protein transportTransport

Technical term

Proteomics identificationReference proteome

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