WASHC3 antibody

• Background:

  Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor(NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting(PubMed:19922875, PubMed:20498093).

• Synonyms:

  WASH complex subunit 3|Coiled-coil domain-containing protein 53|WASHC3

• Gene ID:

  51019

• UniProt:

  Q9Y3C0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  coiled-coil domain containing 53

• Target:

  WASHC3

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

• CAS Number:

  9007-83-4