KDM5C antibody

CAT: 0710-FNab04513Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab04513Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity) .

Synonyms

Gene ID

8242

UniProt

P41229

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Lysine (K) -specific demethylase 5C

Target

KDM5C

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

171-180 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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