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KATNB1 antibody

CAT: 0710-FNab04471Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04471Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
Synonyms
Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) |p80 katanin|KATNB1
Gene ID
10300
UniProt
Q9BVA0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Katanin p80 (WD repeat containing) subunit B 1
Target
KATNB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
72-80 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

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