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KATNA1 antibody

CAT: 0710-FNab04469Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04469Size:100 µg
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Background
Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
Synonyms
Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) |p60 katanin|KATNA1
Gene ID
11104
UniProt
O75449
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Katanin p60 (ATPase-containing) subunit A 1
Target
KATNA1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55-60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

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