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KARS1 antibody

CAT: 0710-FNab04467Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04467Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA (3) (Lys), the primer for reverse transcription initiation.
Synonyms
Lysine--tRNA ligase|Lysyl-tRNA synthetase (LysRS) |KARS1|KARS|KIAA0070
Gene ID
3735
UniProt
Q15046
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Lysyl-tRNA synthetase
Target
KARS1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
68 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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