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Recombinant Human KARS1

CAT: 0710-P5818-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0710-P5818-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
CMTRIB, DFNB89, EC 6.1.1.6, KARS, KARS 1, KARS 2, KARS1, KARS2, KIAA0070, KRS, Lysine tRNA ligase, Lysine--tRNA ligase, LysRS, Lysyl tRNA synthetase, Lysyl-tRNA synthetase, SYK_HUMAN
UniProt
Q15046
Expression Region
63-597
Host
E.Coli
Tag
N-terminal His Tag
Applications
Western Blot, ELISA
Field of Research
Neuroscience, Metabolism
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Lyophilized powder
Reconstitution
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Molecular Weight
58.7 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
The lyophilized protein is stable at -20 °C for up to 1 year. For extended storage, it is recommended to further dilute in working aliquots after reconstitution. The protein solution is stable at ≤ -20 °C for 3 months, or 2-7 days at 2-8 °C under sterile conditions.Avoid repeated freeze/thaw cycle.
Formulation
Lyophilized from a 0.2 μm filtered solution of 10 mM Hepes, 150 mM NaCl with 5% trehalose, pH 7.4.
Organism Species
Human

UniProtKB · Q15046

Lysine--tRNA ligase

SYK_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15046
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KARS1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.7.-, 6.1.1.6
Processing
—
Secondary accessions
A8MSK1, D3DUK4, O14946, Q96J25, Q9HB23
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Molecular function

Aminoacyl-tRNA synthetaseLigaseTransferase

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmMembraneMitochondrionNucleusSecreted

Disease

Charcot-Marie-Tooth diseaseDeafnessDisease variantIntellectual disabilityNeurodegenerationNeuropathyNon-syndromic deafness

Biological process

Host-virus interactionProtein biosynthesis

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