IRF4 antibody

IRF4 antibody

• Background: Transcriptional activator. Binds to the interferon-stimulated response element(ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence(5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes(By similarity).
• Synonyms: Interferon regulatory factor 4 (IRF-4)|Lymphocyte-specific interferon regulatory factor (LSIRF)|Multiple myeloma oncogene 1|NF-EM5|IRF4|MUM1
• CAS Number: 9007-83-4
• Gene ID: 3662
• UniProt: Q15306
• Host: Rabbit
• Reactivity: Human, Mouse
• Immunogen: interferon regulatory factor 4
• Target: IRF4
• Clonality: Polyclonal
• Isotype: IgG
• Applications: ELISA, IHC, WB, IP
• Field of Research: Epigenetics, Cancer, Metabolism
• Purification: Immunogen affinity purified
• Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
• Purity: ≥95% as determined by SDS-PAGE
• Form: Liquid
• Molecular Weight: 52 kDa
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)