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IRF4 antibody

CAT: 0710-FNab04390Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04390Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8 (+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity) .
Synonyms
Interferon regulatory factor 4 (IRF-4) |Lymphocyte-specific interferon regulatory factor (LSIRF) |Multiple myeloma oncogene 1|NF-EM5|IRF4|MUM1
Gene ID
3662
UniProt
Q15306
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Interferon regulatory factor 4
Target
IRF4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IP
Field of Research
Epigenetics, Cancer, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
52 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, IP

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