IL33 antibody

• Background:

  Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016) . Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528) .

• Synonyms:

  Interleukin-33 (IL-33) |Interleukin-1 family member 11 (IL-1F11) |Nuclear factor from high endothelial venules (NF-HEV) |Interleukin-33 (95-270) |Interleukin-33 (99-270) |Interleukin-33 (109-270) |IL33|C9orf26|IL1F11|NFHEV

• Gene ID:

  90865

• UniProt:

  O95760

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Interleukin 33

• Target:

  IL33

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC, WB

• Field of Research:

  Immunology, Cardiovascular

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:1000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  35 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC, WB