IL22RA1 antibody

• Background:

  Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

• Synonyms:

  Interleukin-22 receptor subunit alpha-1 (IL-22 receptor subunit alpha-1, IL-22R-alpha-1, IL-22RA1)|Cytokine receptor class-II member 9|Cytokine receptor family 2 member 9 (CRF2-9)|ZcytoR11|IL22RA1|IL22R

• Gene ID:

  58985

• UniProt:

  Q8N6P7

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  interleukin 22 receptor, alpha 1

• Target:

  IL22RA1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF

• Field of Research:

  Immunology, Cardiovascular, Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  62 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

• CAS Number:

  9007-83-4