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IL1RL2 antibody

CAT: 0710-FNab04246Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04246Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Receptor for interleukin-36 (IL36A, IL36B and IL36G) . After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity) . The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.
Synonyms
Interleukin-1 receptor-like 2|IL-36 receptor (IL-36R) |Interleukin-1 receptor-related protein 2 (IL-1Rrp2, IL1R-rp2) |IL1RL2|IL1RRP2
Gene ID
8808
UniProt
Q9HB29
Host
Rabbit
Reactivity
Human
Immunogen
Interleukin 1 receptor-like 2
Target
IL1RL2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, FC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
65 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, FC