IL1RL2 antibody

• Background:

  Receptor for interleukin-36 (IL36A, IL36B and IL36G) . After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity) . The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.

• Synonyms:

  Interleukin-1 receptor-like 2|IL-36 receptor (IL-36R) |Interleukin-1 receptor-related protein 2 (IL-1Rrp2, IL1R-rp2) |IL1RL2|IL1RRP2

• Gene ID:

  8808

• UniProt:

  Q9HB29

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Interleukin 1 receptor-like 2

• Target:

  IL1RL2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, FC

• Field of Research:

  Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:1000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  65 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, FC