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IL1RAPL1 antibody

CAT: 0710-FNab04245Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04245Size:100 µg
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Background
May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in presynaptic and postsynaptic differentiation and dendritic spine formation in neurons.
Synonyms
Interleukin-1 receptor accessory protein-like 1 (IL-1-RAPL-1, IL-1RAPL-1, IL1RAPL-1) |Oligophrenin-4|Three immunoglobulin domain-containing IL-1 receptor-related 2 (TIGIRR-2) |X-linked interleukin-1 receptor accessory protein-like 1|IL1RAPL1|OPHN4
Gene ID
11141
UniProt
Q9NZN1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Interleukin 1 receptor accessory protein-like 1
Target
IL1RAPL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
66-75 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP

UniProtKB · Q9NZN1

Interleukin-1 receptor accessory protein-like 1

IRPL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NZN1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL1RAPL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-1-RAPL-1, IL-1RAPL-1, IL1RAPL-1
EC number
3.2.2.6
Processing
Precursor
Secondary accessions
A0AVG4, Q9UJ53
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCell projectionCytoplasmMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

HydrolaseReceptor

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Disease

Intellectual disability

Ligand

NAD

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