IGSF8 antibody

• Background :

  May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

• Synonyms :

  Immunoglobulin superfamily member 8 (IgSF8) |CD81 partner 3|Glu-Trp-Ile EWI motif-containing protein 2 (EWI-2) |Keratinocytes-associated transmembrane protein 4 (KCT-4) |LIR-D1|Prostaglandin regulatory-like protein (PGRL) |IGSF8|CD81P3|EWI2|KCT4

• Gene ID :

  93185

• UniProt :

  Q969P0

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Immunoglobulin superfamily, member 8

• Target :

  IGSF8

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IP

• Field of Research :

  Immunology, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IP: 1:200-1:2000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  70 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IP

• Immunogen Sequence :

  28-350aa