IGSF8 antibody

• Background:

  May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

• Synonyms:

  Immunoglobulin superfamily member 8 (IgSF8) |CD81 partner 3|Glu-Trp-Ile EWI motif-containing protein 2 (EWI-2) |Keratinocytes-associated transmembrane protein 4 (KCT-4) |LIR-D1|Prostaglandin regulatory-like protein (PGRL) |IGSF8|CD81P3|EWI2|KCT4

• Gene ID:

  93185

• UniProt:

  Q969P0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Immunoglobulin superfamily, member 8

• Target:

  IGSF8

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IP

• Field of Research:

  Immunology, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:200-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  70 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IP

• Immunogen Sequence:

  28-350aa